Visionblue
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Questions & Answers
Side Effects & Adverse Reactions
There is currently no warning information available for this product. We apologize for any inconvenience.
Legal Issues
There is currently no legal information available for this drug.
FDA Safety Alerts
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Manufacturer Warnings
There is currently no manufacturer warning information available for this drug.
FDA Labeling Changes
There are currently no FDA labeling changes available for this drug.
Uses
VisionBlue™ is indicated for use as an aid in ophthalmic surgery by staining the anterior capsule of the lens.
History
There is currently no drug history available for this drug.
Other Information
VisionBlue™ (trypan blue ophthalmic solution) 0.06% is a sterile solution of trypan blue (an acid di-azo group dye). VisionBlue™ is a selective tissue staining agent for use as a medical aid in ophthalmic surgery.
Each mL of VisionBlue™ 0.06% contains: 0.6 mg trypan blue; 1.9 mg sodium mono-hydrogen orthophosphate (Na2HPO4.2H2O); 0.3 mg sodium di-hydrogen orthophosphate (NaH2PO4.2H2O); 8.2 mg sodium chloride (NaCl); and water for injection. The pH is 7.3 - 7.6. The osmolality is 257-314 mOsm/kg.
The drug substance trypan blue has the chemical name 3,3’-[(3,3’-dimethyl-4,4’-biphenylylene) bis (azo)] bis(5-amino-4-hydroxy-2,7-naphthalenedisulfonic acid) tetra sodium salt, a molecular weight of 960.8, a molecular formula of C34H24N6Na4O14S4, and has the following chemical structure:
Sources
Visionblue Manufacturers
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Dutch Ophthalmic Research Center International B.v.
![Visionblue (Trypan Blue) Injection, Solution [Dutch Ophthalmic Research Center International B.v.]](/wp-content/themes/bootstrap/assets/img/loading2.gif)
Visionblue | Dutch Ophthalmic Research Center International B.v.
Cataract surgery
VisionBlue™ is packaged in a 2.25 mL syringe to which a blunt cannula has to be attached.
After opening the eye, an air bubble is injected into the anterior chamber of the eye in order to minimize dilution of VisionBlue™ by the aqueous. VisionBlue™ is carefully applied onto the anterior lens capsule using a blunt cannula. Sufficient staining is achieved as soon as the dye has contacted the capsule. The anterior chamber is then irrigated with balanced salt solution to remove all excess dye. An anterior capsulotomy can then be performed.
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