Merial, Inc.

Merial, Inc. Drugs

• Marquis Antiprotozoal
  

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  Marquis Antiprotozoal

  

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  DOSAGE: Administer MARQUIS at a dose of 15 mg/kg (6.81 mg/lb) body weight as a loading dose for the first dose only. The loading dose is followed by a maintenance dose of 5 mg/kg (2.27 mg/lb) body weight once daily for a period of 27 additional days.

  Day 1: Administer a loading dose of 15 mg/kg (three times the maintenance dose) once by mouth. Because the dosage ring is calibrated by weight for the maintenance dose (5mg/kg), adjust the dosage ring to the appropriate weight and administer this 5 mg/kg dose orally, three consecutive times for a total dose of 15 mg/kg.

  Day 2 through 28: Administer the maintenance dose of 5 mg/kg once daily by mouth.

  ADMINISTRATION:

  Paste syringe assembly:Before administration, the syringe barrel and plunger require assembly. Ensure plunger is clean and dry. Step 1. End cap must be on syringe barrel when inserting plunger. Step 2. Carefully insert reusable plunger into base of syringe barrel until it snaps into place, then remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Step 3. Return end cap to tip of paste syringe. Administering MARQUIS to the horse: NOTE: The paste syringe is a multi-dose package. Ensure that the correct dose is administered with each use. For the first dose only, complete steps 3 through 6 three times, then continue with steps 7 and 8. Step 1. Remove end cap and gently apply pressure to the plunger until paste is seen at the tip of the syringe barrel. Return end cap to tip of paste syringe. Step 2. Determine weight of horse and ensure the horse's mouth contains no feed. Step 3. To measure dose, dosage ring collar and barrel collar should be flush. Hold plunger and rotate dosage ring with the other hand to the weight of the horse. Step 4. Remove end cap from tip of syringe barrel. Step 5. The selected dose of paste should be deposited onto the back and top of the horse's tongue. Introduce tip of paste syringe into the side of the horse's mouth at the space between the front (incisor) and back (molar) teeth. Deposit paste on the horse's tongue by depressing the plunger of the syringe as far as the dose ring permits. Remove tip of syringe from horse's mouth. Step 6. To aid swallowing of paste, immediately raise horse's head for a few seconds after dosing. Step 7. Clean the tip of the syringe with a clean disposable towel and return end cap to tip of syringe barrel. Step 8. For the next daily dose, repeat steps 1-7. NOTE: At the end of the prescribed treatment period, partially used syringes should be discarded.

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• Legend
  

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  Legend

  

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  DOSAGE AND ADMINISTRATION:

  Intravenously-4 mL (40 mg), Intra-articular- 2 mL (20 mg) in the carpus or fetlock. Treatment may be repeated at weekly intervals for a total of three treatments.

  Strict aseptic technique should be observed when administering by intra-articular injection. As with any intra-articular procedure, proper injection site disinfection and animal restraint are important. Excess joint fluid should be aseptically removed prior to injection. Care should be taken to avoid scratching the cartilage surface with the tip of the injection needle. Diffuse swelling lasting 24 to 48 hours may result from movement of the needle while in the joint space.

  For intravenous administration, use aseptic technique and inject slowly into the jugular vein.

  Horses should be given stall rest after treatment before gradually resuming normal activity.

  Discard any unused portion of the drug and the empty vial after opening.

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• Legend Multi Dose
  

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  Legend Multi Dose

  

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  DOSAGE AND ADMINISTRATION:

  4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.

  Use aseptic technique and inject slowly into the jugular vein.

  Horses should be given stall rest after treatment before gradually resuming normal activity.

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• Legend
  

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  Legend

  

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  DOSAGE AND ADMINISTRATION:

  4 mL (40 mg) injected intravenously. Treatment may be repeated at weekly intervals for a total of three treatments.

  Use aseptic technique and inject slowly into the jugular vein.

  Horses should be given stall rest after treatment before gradually resuming normal activity.

  Discard any unused portion of the drug and empty vial after opening.

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