Tobradex

Tobradex

Tobradex Recall

Get an alert when a recall is issued.

Questions & Answers

Side Effects & Adverse Reactions

NOT FOR INJECTION INTO THE EYE. Sensitivity to topically applied aminoglycosides may occur in some patients. If a sensitivity reaction does occur, discontinue use.

Prolonged use of steroids may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. Intraocular pressure should be routinely monitored even though it may be difficult in pediatric patients and uncooperative patients. Prolonged use may suppress the host response and thus increase the hazard of secondary ocular infections. In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids. In acute purulent conditions of the eye, steroids may mask infection or enhance existing infection.

Legal Issues

There is currently no legal information available for this drug.

FDA Safety Alerts

There are currently no FDA safety alerts available for this drug.

Manufacturer Warnings

There is currently no manufacturer warning information available for this drug.

FDA Labeling Changes

There are currently no FDA labeling changes available for this drug.

Uses

TOBRADEX (tobramycin and dexamethasone ophthalmic ointment) is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists.

Ocular steroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe where the inherent risk of steroid use in certain infective conjunctivitides is accepted to obtain a diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation or thermal burns, or penetration of foreign bodies.

The use of a combination drug with an anti-infective component is indicated where the risk of superficial ocular infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye.

The particular anti-infective drug in this product is active against the following common bacterial eye pathogens:

Staphylococci, including S. aureus and S. epidermidis (coagulase-positive and coagulase-negative), including penicillin-resistant strains.

Streptococci, including some of the Group A-beta-hemolytic species, some nonhemolytic species, and some Streptococcus pneumoniae.

Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus influenzae and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species.

History

There is currently no drug history available for this drug.

Other Information

TOBRADEX® (tobramycin and dexamethasone ophthalmic ointment) is a sterile, multiple dose antibiotic and steroid combination for topical ophthalmic use. The chemical structures for tobramycin and dexamethasone are presented below:

Chemical Structures

Each gram of TOBRADEX® (tobramycin and dexamethasone ophthalmic ointment) contains: Actives: tobramycin 0.3% (3mg) and dexamethasone 0.1% (1mg). Preservative: chlorobutanol 0.5%. Inactives: mineral oil and white petrolatum.

Tobradex Manufacturers


  • Rebel Distributors Corp
    Tobradex (Tobramycin And Dexamethasone) Ointment [Rebel Distributors Corp]
  • Rebel Distributors Corp
    Tobradex (Tobramycin And Dexamethasone) Suspension [Rebel Distributors Corp]
  • Alcon Laboratories, Inc.
    Tobradex (Tobramycin And Dexamethasone) Ointment [Alcon Laboratories, Inc.]
  • Alcon Laboratories, Inc.
    Tobradex (Tobramycin And Dexamethasone) Suspension [Alcon Laboratories, Inc.]
  • Stat Rx Usa Llc
    Tobradex (Tobramycin And Dexamethasone) Suspension [Stat Rx Usa Llc]
  • A-s Medication Solutions Llc
    Tobradex (Tobramycin And Dexamethasone) Suspension [A-s Medication Solutions Llc]
  • A-s Medication Solutions Llc
    Tobradex (Tobramycin And Dexamethasone) Suspension [A-s Medication Solutions Llc]
  • A-s Medication Solutions Llc
    Tobradex (Tobramycin And Dexamethasone) Ointment [A-s Medication Solutions Llc]

Login To Your Free Account